Insulin resistance may cause faster cognitive decline

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Insulin resistance, caused in part by obesity and physical inactivity, is also linked to a more rapid decline in cognitive performance, researchers say.

Insulin resistance is a condition in which cells fail to respond normally to the hormone insulin. The resistance prevents muscle, fat, and liver cells from easily absorbing glucose. As a result, the body requires higher levels of insulin to usher glucose into its cells.

The study, appearing in the Journal of Alzheimer’s Disease, showed that both diabetic and non-diabetic subjects with insulin resistance experienced accelerated cognitive decline in cognitive functions such as memory, executive function, visual spatial processing, and attention.

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