Treatment for cystic fibrosis may cause hearing loss

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The antibiotics administered may affect the hearing of the patients already receiving treatment for the disease

New York: High dosage of a powerful class of antibiotics administered to treat cystic fibrosis may significantly increases the risk of permanent hearing loss, a
new study has warned.

Cystic fibrosis (CF) is an inherited life-threatening disorder that damages the lungs and digestive system. About 70,000 people worldwide are living with the disease.The study by researchers from Oregon Health & Science University in the US suggests physicians who treat patients with cystic fibrosis may be able to consider alternative strategies for treating the symptoms of respiratory infections associated with CF, especially if patients are responsive to different classes of antibiotics.

“Preventing or ameliorating the effects of permanent hearing loss is crucial for patients with CF who already have a significantly compromised quality of life due to the disease,” researchers said. The medical records of 81 CF patients, aged 15 to 63 years was examined. These patients were further grouped into
four quartiles based on the cumulative dosage of aminoglycoside antibiotics administered intravenously.

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